Of 87,984 US participants who completed the baseline survey and provided data on tobacco and cannabis use, 53,843 participants (response rate of 61.2%) who completed at least one monthly survey on mental health were included in this analysis.
Tobacco and cannabis are among the most commonly used substances worldwide. In the U.S., 22.1% of adults reported using tobacco and 12.4% using cannabis in the past month in 2020.
Overall, 4.9% of participants reported using only tobacco, 6.9% only cannabis, and 1.6% using it jointly.
Among US adults in the co-consumption group, 26.5% reported anxiety and 28.3% reported depression, while among people who did not use either of these substances the percentages of anxiety and depression were 10.6% and 11.2%, respectively.
The study found that the likelihood of suffering from these mental health disorders was approximately 1.8 times higher for co-users than for non-users.
Co-use and exclusive cannabis use were also associated with an increased likelihood of having anxiety compared to exclusive tobacco use.
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