Romney is known in the Senate as a frequent bipartisan negotiator and was the only Senate Republican to vote twice to convict former President Trump following separate impeachment trials.
Romney, 76, noted in a video statement that he would be in his mid-80s by the end of another term and said he is opting to make way for new voices.
“While I’m not running for reelection, I’m not retiring from the fight,” he said.
But, he said, “it’s time for a new generation of leaders. They’re the ones that need to make the decisions that will shape the world they will be living in.”
Romney has spent more than 25 years working in public service, including as the Republican Party’s nominee for president in 2012. His announcement comes as Republicans aim to retake control of the Senate next year.
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